Hi Lawrence,
I wanted to
ask you to help me spread, among your friends and people that you know, this web
page for crowd funding for a research project on chronic lymphocytic leukemia
(CLL in English or LLC in Spanish). This project has been selected together
with other nine projects and is endorsed by the Sociedad Española de
Inmunología (SEI). You know that the state budget for research is very small in
Spain and the SEI proposed to resort to crowd funding.
My project
is to try and understand why B cells get malignant in the CLL. CLL is one of
the more frequent leukemia developed in adult people.
In healthy
people, only 5-10% of B cells express PSGL-1, but we have found that most B
lymphocytes from people with Chronic Linfocitic Leukemia express this protein
PSGL-1. We think that this protein contributes to the malignancy of B
lymphocytes, helping them to proliferate, to invade different tissues and to
kill T cells and, in addition, impairing them to produce antibodies against
microbes. Our project can help know the molecular mechanisms altered in the CLL
B cells and hence to find new molecular targets for more effective disease
treatment.
The link to my research project is:
Thank you very much Lawrence!!
Best
Ana
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